Ranitidine causes cancer

Medicines recall: Authority warns of some gastric acid blockers because of the risk of cancer

They are prescribed for heartburn, reflux diseases and for the prophylaxis of gastric ulcers: many patients take gastric acid blockers every day.

Cancer risk: gastric acid blocker from several manufacturers recalled

But caution is advised: The Federal Institute for Drugs and Medical Devices is currently warning against drugs that contain ranitidine. Tests have shown that some of these products are contaminated and could cause cancer. Medicines with ranitidine may contain the impurity N-nitrosodimethylane (NDMA), which in higher amounts causes cancer.

Medicines containing ranitidine are widely used to reduce the production of stomach acid in patients with conditions such as heartburn and stomach ulcers. They are available both without a prescription and with a prescription.

In order not to take any risks, preparations from several pharmaceutical manufacturers are now being recalled due to suspected contamination with carcinogenic substances.

Betapharm Arzneimittel GmbH

  • Ranibeta 300
    50 and 100 film-coated tablets
    Ch.-B .: C700074, C700076, C700078
    (PZN 07280238 and 07280244)

Hexal AG

  • Ranitic 75 mg for acute heartburn
    14 film-coated tablets
    All batches
    (PZN 03567925)
     
  • Ranitic 150 mg and 300 mg
    20, 50 and 100 film-coated tablets
    All batches
    (PZN 07277495, 07277503 and 07277526)
    (PZN 07277532, 07277549 and 07277555)

1 A Pharma GmbH

  • Ranitidine 75 - 1 A Pharma
    10 and 14 film-coated tablets
    All batches
    (PZN 01694542 and 03711888)
     
  • Ranitidine 150 and 300 - 1 A Pharma
    20, 50 and 100 film-coated tablets
    All batches
    (PZN 08533960, 08533977 and 08533983)
    (PZN 08534008, 08534014 and 08534020)

AbZ Pharma GmbH

  • Ranitidine 150 and 300mg - AbZ
    50 and 100 film-coated tablets
    All batches with an expiry date until 06/2021

Ratiopharm

  • Ranitidine 150 and 300mg - Ratiopharm
    50 and 100 film-coated tablets
    All batches with an expiry date until 06/2021
  • Ranitidine 50mg / 5ml - Ratiopharm
    5x5 ml solution for injection
    All batches with an expiry date until 06/2021

Mylan Germany

  • Ranidura 150 and 300 mg
    20, 50 and 100 film-coated tablets
    All batches with an expiry date until 02/2022

According to the authorities and the manufacturer, an acute patient risk cannot be assumed after taking the medication concerned. Pharmacists will now check their stocks in order to take the drugs off the market.